Artificial liver device Research Paper Example | Topics and Well Written Essays - 1250 words

Artificial colorful device - Research Paper pillow slipAlthough the results were promising, in depth research is fluent needed to reconcile regulatory standards with the processes employed in apply ALDs as well as to determine other sources of cell line, and other methods for prolonging cell line viability. insertion The liver is the largest organ in the body. It has a myriad of functions storage of glycogen synthesis of glucose from fat and protein stores detoxification of rip protein synthesis bile production to aid fat digestion voiding of end products of protein metabolism synthesis, breakdown and convention of hormones and antibody production among others. All these work together to maintain homeostasis, and enable the different body systems to function optimally. continuing liver disease (e.g. cirrhosis) is the seventh leading cause of death in the US with approximately 27,000 wad dying from it annually (Liver Disease Statistics n.pag. Liver Disease Statistics n.pag.) . check to the Center for Disease Control, active 112,000 people discharged from in-patient c atomic number 18 are diagnosed with liver diseases (Chronic Liver Disease or cirrhosis of the liver n.pag.). ... It can cause symptoms such as edema and jaundice as well as aggregation of metabolic waste products, such as urea, eventually poisoning the different organs especially the brain. According to Pareja et al., the most effective treatment for...patients with chronic liver failure are orthotropic liver transplantation... (n.pag.). However, giver liver is of throttle supply and may take weeks, months or even years, before a viable organ donor is available. In a survey conducted by the Center for Liver Disease and Transplantation, approximately 17,000 people are waiting for a liver transplant in the US with an approximate waiting time of 321 eld (Liver Transplantation Patient Guide The Waiting List n.pag.). Liver failure is coupled with a high death rate in the absence of transp lantation (Carpentier et al. 1690). Apart from transplantation, researchers are exploring other alternatives in treating chronic liver disease. Among these are the uses of artificial and bio-artificial liver devices that will take into account transient support for failing livers. Artificial liver (AL) devices make use of machines to rid the blood or plasma of toxins and by-products of metabolism (Carpentier et al. 1690). Bio-artificial liver (BAL) devices, on the other hand, make use of cell lines housed in a bioreactor cartridge that perform the detoxification, biotransformation, excretion and synthetic function of the liver (Carpentier et al. 1690). Availability of these devices, however, has not reached the market as more studies are still being done in order to reconcile the different issues associated with its widespread use. Method Bio-artificial liver devices provide liver assistance continuously for thirty days, enabling the patients liver to heal, or to